Louise Mott studied at the Guildhall School of Music and the Royal College of Music, before completing her training at the National Opera Studio.

Louise made her débuts at English National Opera as Bradamante Alcina, Welsh National Opera as Annio La Clemenza di Tito and Opera North as Annina Der Rosenkavalier, followed by Fidalma Il matrimonio segreto. She sang Ariodante for English Touring Opera and Mme Larina Eugene Onegin for Scottish Opera on Tour. For the Early Opera Company she has sung Edith Alfred (Thomas Arne), Agrippina, Ruggiero Alcina, Ariodante, Sesto Giulio Cesare, Orlando, Rosmira Partenope, Melissa Amadigi, Serse and Dido Dido and Aeneas. Other roles include Meg Page Falstaff for Diva Opera and Pfalztheater Kaiserslautern, Second Lady The Magic Flute and Marcellina Marriage of Figaro for Opera Project, Katarina Schratt Mayerling for The Royal Balletat The Royal Opera House.

Contemporary opera performances include for Almeida Opera: Ion (Param Vir), God's Liar (John Casken) and Marguerite Hey, Persephone! (Deidre Gribbin) and Marlinchen The Juniper Tree (Roderick Watkins), also at the Muffathalle, Munich; for The Opera Group: Emerald Boys and Girls Come Out to Play (Holloway) and Blind Mary The Martyrdom of St Magnus, Penelope Linen from Smyrna(Edward Rushton) and Cordula Wagner The Shops (Edward Rushton) at the Bregenz Festival and in the Linbury, Royal Opera House; for Tête à Tête: Penelope in Odysseus Unwound, Angela in Push (David Bruce) and Lite Bites (The Opera Festival). Other performances have included Blind Mary The Martyrdom of St Magnusat the Oslo Kammermusik Festival and with the Hebrides Ensemble at the Orkney Festival, Marcella Alban (Tom Wiggall) at St Albans Abbey and Wife/Sphinx/Doreen Greek (Mark-Anthony Turnage) with the London Sinfonietta.

Recent engagements have included Mozart's Requiem and Solemn Vespers for the Bach Choir and the OAE at the Royal Festival Hall, London, Fricka, Erda, Flosshilde and Gutrune in EPOC's Pocket Ring Cycle, Priestess Seven Angels (Luke Bedford) for The Opera Group, Praskowia The Merry Widow for Opera Project, Marquise Berkenfield La Fille du Regiment, Count Orlofsky Die Fledermaus Party Scene and Second Lady Die Zauberflöte for Diva Opera in the UK and on tour in Europe and Helen King Priam at the Brighton Festival. 

Engagements for 2013 include 2nd Witch (& Dido cover) Dido and Aeneas for Opera North, La Frugola Il tabarro & La Ciesca Gianni Schicchi for Caledonian Opera at Haddo House Hall, Dido Dido and Aeneas for St Albans Chamber Opera and Flora Bervoix La Traviata for Diva Opera.